At the core of the Chrometra technology lies the realization that nature has developed tools for the specific modification of biomolecules, called enzymes, and significant opportunities for biotechnology can be found by making these enzymes work to our advantage.
Chrometra develops combinations of small molecules and enzymes to specific target biomolecules such as DNA, RNA and proteins, for use in biotechnology and diagnostics. This translates the enzyme specificity into robust components for biotechnology.
Some of the major advantages of the Chrometra platform are gentle modification in biological environment, highly specific modification which allows you to account for location information and versatility through the combination of organic chemistry and chemical biology.
Through post-synthetic polynucleotide labeling, the power of the unique DNA or RNA code can be harnessed in assays of diagnostic applications, with typical applications of such DNA/RNA modification as fluorescence in situ hybridization (FISH), in DNA/RNA sequencing or microarray based genetic analysis.
The underlying design principles of these techniques can be roughly segmented into two: chemical labeling and enzymatic labeling, both associated with advantages and disadvantages.
Building on extensive R&D experience, we can help you select the best possible approach to tackle your problem in assay development or genetic technology. Feel free to get in touch!